Corrupted Prison

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Corrupted Confinement is a short, optional biome between the second and the third level. It's accessed through Toxic Sewers using the Spider rune and leads to the Ancient Sewers or the Ramparts (1+ BSC).

Because of the last update decreasing the amount of Cursed Chests, in the first room of this biome there is always a guaranteed one. To the right of the chest there is a door that will close behind the Beheaded, no matter if he had or hadn't layed the curse upon himself.

Presumably the most dangerous and lethal enemy of the Corrupted Confinement is the Slammer, as (for such an early biome) he has very high DPS, and a bigger than average amount of HP.