Mutations

Mutations, introduced in the Foundry Update, are passive modifiers which replace Stat-based secondary effects from the Brutal Update. They can be obtained between levels from Guillain.

Most mutations are not available initially - to unlock them for future selection, one must first bring their blueprints to the Collector, then spend the requisite amounts of cells.

Mechanics
The player can only benefit from a certain number of mutations at once. Each area cleared in a run allows the player to use one more mutation up to a hard limit of 3 mutations. However, the player can choose to spend gold between levels (cost starts at 2500 and scales with loot level) to remove all current mutations, allowing for a new set of mutations to be chosen to replace the old set.

Most mutations are associated with a specific stat (Brutality, Tactics or Survival), scaling their benefits based on their current levels. Specifically, base damage and healing magnitudes for these mutations are multiplied by (1.15^(n-1)), where n is the current level of the appropriate stat, and rounded to produce the final effect magnitudes (e.g. if a Brutality-scaling mutation provides 90 base extra DPS and the player's Brutality level is at 2, the final extra DPS is (90 × (1.15^(2-1))) = 90 × 1.15 = 103.5 ≈ 104). Note that damage and DPS bonuses on attacks from mutations are not affected by gear-specific damage bonuses or Affixes.

General mutations, however, have fixed benefits which are not affected by the player's stat levels, and the cooldown-reduction mutation has its own unique scaling with Tactics.

Brutality Mutations
Fireworks Technician's scaling with Brutality is given in the following table:

Tactics Mutations
Efficiency's scaling with Tactics is given in the following table: