Pickups

Pickups are items which are not gear, stat upgrade scrolls, runes, or blueprints. Pickups can be collected with the Interact command while the player is close or, in the case of gems, just by walking on top of them.

All main categories of pickups are:


 * Gems worth varying amounts of gold.
 * Food that heals the player.
 * Scrolls to upgrade player stats.
 * Cells used to unlock and upgrade mechanisms and items.
 * Specials serving miscellaneous functions.
 * Keys which let the player unlock doors.

Gems
Gems give a significant amount of gold when collected. Gems are more valuable when appearing in harder biomes, and their value increases with each loot level rounded to the nearest multiple of 5.

Food
Food regenerates a fixed percentage of health when eaten (or twice as much if the Gastronomy mutation is active). There are 2 different functional types of food, each with 7 different appearances depending on the selected diet, which is altered by game settings. If untouched by the player, it will be chosen as "Carnivore."

Minor Foods
Minor foods restore 15% of the player's maximum health (30% if Gastronomy is active). They're found in enemies, wall and floor runes, and food shops.

Major Foods
Major foods heal 50% of the player's maximum health (100% if Gastronomy is active). They're found in the same ways minor foods are, as well as in lore rooms, but are rarer.

Scrolls
Scrolls are items that increase player stats.

Cells
Cells are one of two currencies in the game. They're often dropped from slain enemies, or found in chests and capsules in biomes. They are responsible for permanent upgrades.

It is worth noting that all cells are lost on death.

Cells can be spent in two ways; unlocking blueprints and upgrades at The Collector, or increasing item quality at The Blacksmith's Legendary Forge.

Dead Man’s Bag


A bag that spawns at the start of Prisoners' Quarters. It contains some of the gold from your last run. The value depends on your current level of Gold Reserves and any gold above this limit is lost.

Residual Cells


A bag that spawns next to the Dead Man's Bag if you defeated The Hand of the King. It contains any cells possessed upon reaching the Throne Room, as well as the 40 cells dropped by the Hand of the King. If not picked up, or if the run is reset, the cells will be lost.

Scroll Fragments


Scroll Fragments are found in 3BSC+. They're either picked up from Scroll Fragment altars in biomes or dropped when a boss is slain. Collecting four of them allows you to upgrade one of your three stats.

Liposuction


A rare pickup that produces one extra cell on every kill for 45 seconds, even if the enemy doesn't normally drop cells. It randomly drops from enemies, but the exact chance is unknown.

Cough Syrup


Reduces Malaise infection levels by 30%. Can be bought at food shops.

Bonus Point Stars


Bonus Point Stars are exclusively found in the Daily Run. They give a 5-point bonus for each enemy killed for 15 seconds.

Keys
Unlike most pickups, keys are not used when they are picked up. Instead, they are added to the player's inventory, so they can be used later to open their respective doors. Keys remain in the player's inventory for the rest of the run if not used on the appropriate door. Unused keys disappear upon death or at the end of a successful run.