The Machete and Pistol is a meleeweapon with a three part combo.
For the first two attacks of the combo, the machete is used.
The third attack in the combo deals critical damage, knocks back enemies, and inflicts a fire status effect.
The pistol's blast has a greatly extended hitbox which does damage in a cone shape. This third attack is useful for crowd control, flying enemies, and finishing off enemies who are out of range of the machete.
In the Prisoners' Quarters, there is a chance for a lore room to spawn with an altar. Examining this altar will drop this item. Upon doing so, player will be cursed with a one-kill curse. Picking the item up will instantly unlock it.
"So menacing! Should I really search it?"
"Oh, it's not like it's cursed or anything."
Like some other weapons, this weapon's combo can be offset by a dodge or a parry, allowing the player to change position before unleashing the pistol.
As such, this weapon is well suited to hit-and-run strategies, and pairs well with ranged weapons that also scale with Tactics.
Although the last hit of the combo appears to be ranged, the game recognizes it as a melee attack. Therefore, it can trigger relevant mutations such as Melee or Open Wounds.
This weapon functions similarly to the Twin Daggers in that the third attack of the combo deals critical damage.